TUM
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EMBO Practical Course:

Structure, dynamics and function of biomacromolecules by solution NMR

The intention of the course is to provide practical training in important aspects of using solution state NMR spectroscopy for studying the structure, dynamics and function of biomolecular macromolecules. The emphasis will be on setting up experiments on the spectrometer (optimizing parameters, pulse programs), on processing and analyzing the NMR data and on structure calculations in a hands-on fashion.
It is impossible to teach all the necessary theoretical background of modern NMR experiments in a few days. Therefore, the course is aimed at PhD students and postdocs who have some working knowledge of NMR theory, i.e. product operator formalism, and who understand the basic principles of NMR pulse sequences. Possible candidates should have the level of knowledge of students that have participated in a past "Advanced NMR" EMBO lecture course on NMR theory organized by Boelens, Oschkinat and Griesinger.


Organizers
Stephan Grzesiek (Biozentrum Basel)
Michael Nilges (Institut Pasteur, Paris)
Michael Sattler (TU München, Helmholtz Zentrum München)





EMBO poster



Sponsors:

EMBO

Bruker
EurisotopSigma-Aldrich IsoteccortecnetSilantes

Logos

Location        BNMRZ, Department Chemie, TU München; Garching (Germany)
Date               Jul 29 - Aug 5, 2011

Programme
  Final Programme

Lectures       Lecture notes and practical manuals
                       Login details have been provided to participants.

Literature       Recommendations from the instructors (request from Round Table)

Photos          Please send any (digital) photos you may have for posting here to Gerd or Michael.
                       A first selection of pictures from participants can be found here.  
To be updated!
                       
Registration  EMBO (registration)  (Registration is closed)
                       There will be a fee of 250 EUR for accepted participants, which covers lodging, food, workshop dinner etc.
 
                     Accepted participants have been notified.

Contact         Michael Sattler  sattler@helmholtz-muenchen.de 

Subway schedule  Hotel --> TUM     TUM--> Hotel

Hotel
All participants and instructors will be staying in the Hotel Ludwig in Garching.
The hotel  is only one stop (by subway U6) from the Department Chemie at the Garching campus of TUM, where the course is held.

Travel  
How to get to the Bavarian NMR Center
Please follow the directions to the BNMRZ at the TUM Garching campus. 
Signs with the EMBO logo will direct you to the seminar room where the course will start on Fri July 29, 13:30 in Room 53301 (yellow cross).

Travel grants Can be applied for to support participants from certain countries (eligibility see here).
                        Accepted participants have been informed).                      

Instructors
Martin Blackledge (IBS Grenoble)
Bernhard Brutscher (IBS Grenoble)
Frank Delaglio (NIH, Bethesda)
Steffen Glaser (TU München)
Peter Güntert (U Frankfurt)
Christian Griesinger (MPI Göttingen)
Stephan Grzesiek (Biozentrum Basel)
Helen Mott (U Cambridge)
Daniel Nietlispach (U Cambridge)
Michael Nilges (Institut Pasteur, Paris)
Roland Riek (ETH Zurich)
Michael Sattler (TU München, Helmholtz Zentrum München)
Harald Schwalbe (U Frankfurt)
Bernd Simon (EMBL Heidelberg)
Nico Tjandra (NIH, Bethesda)
Geerten Vuister (U Leicester)

Tutors
Benjamin Bardiaux (FMP Berlin/Institut Pasteur, Paris)
Sonja Dames (TU München)
Gerd Gemmecker (Bavarian NMR Centre, TU München/Helmholtz Zentrum München)
Rainer Haessner (Bavarian NMR Centre, TU München/Helmholtz Zentrum München)
Henry Jonker (U Frankfurt)
Therese Malliavin (Institut Pasteur, Paris)

Topics
• Pulse sequences: theory, design, practical set-up and use
• Multidimensional data processing and data analysis
• Relaxation: theory, experiments, data analysis
• Residual dipolar and J-couplings: theory, experiments, data analysis
• Structure calculation and validation: proteins and RNA
• Protein-ligand interactions
• High molecular weight systems, TROSY, CRINEPT, etc.
• Advanced/fast data acquisitionand processing