Daniilidis M, Günsel U, Broutzakis G, Leitl KD, Janowski R, Fredriksson K, Niessing D, Gatsogiannis C, Hagn F (2025)
Structural basis of apoptosis induction by the mitochondrial voltage-dependent anion channel.
Nature communications, Issue 1, Vol. 16, 9481
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Bostock MJ, Kolloff C, Jerschke E, Asami S, Skerra A, Olsson S, Sattler M (2025)
Conformational Quenching in an Engineered Lipocalin Protein Achieves High Affinity Binding to the Toxin Colchicine.
Angewandte Chemie (International ed. in English), e202515950
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Walter A, Kuttenlochner W, Eisenreich W, Yao C, Groll M, Storch G (2025)
Studies of α',β'-Epoxyketone Synthesis by Small-Molecule Flavins and Flavoenzymes.
Angewandte Chemie (International ed. in English), e202512568
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Klimenko V, Reiners J, Applegate V, Reimann K, Popowicz G, Hoeppner A, Papadopoulos A, Smits SHJ, Nowack ECM (2025)
The Paulinella chromatophore transit peptide part2 adopts a structural fold similar to the γ-glutamyl-cyclotransferase fold.
Plant physiology
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Akinyi MV, Yao W, Zeman J, Hipp C, Bartsch D, Heaven L, Le Roux CA, Starner AC, Yuan F, Bartels MD, Zhao F, Ha HL, Sharma R, Choudhary B, Biayna J, Brandes RP, Dumbović G, Ray A, Wittig I, Muench C, Sattler M, Van Nostrand EL, Kurian L (2025)
QKI ensures splicing fidelity during cardiogenesis by engaging the U6 tri-snRNP to activate splicing at weak 5' splice sites.
bioRxiv : the preprint server for biology
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Hagl B, Spielberger BD, Neumann B, Pelham SJ, Pandey D, Schlundt A, Barro C, Lechner A, Wolf C, Deenick EK, Sattler M, Tangye SG, Rothenfusser S, Renner ED (2025)
Signal Transducer and Activator of Transcription 3 (STAT3) Variant p.K709N Causes Hyper-IgE Syndrome Likely by Impaired STAT3-Dimer Formation.
European journal of immunology, Issue 7, Vol. 55, e70015
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Pérez-Ràfols A, Pérez-Ropero G, Cerofolini L, Sperotto L, Roca-Martínez J, Higuera-Rodríguez RA, Russomanno P, Kaiser W, Vranken W, Danielson UH, Provenzani A, Martelli T, Sattler M, Buijs J, Fragai M (2025)
Deciphering the RNA recognition by Musashi-1 to design protein and RNA variants for in vitro and in vivo applications.
Nucleic acids research, Issue 15, Vol. 53
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Kale OE, Hu S, Huber C, Schierholz F, Ciotkowska A, Tamalunas A, Stief CG, Eisenreich W, Hennenberg M (2025)
Acridocarpus smeathmannii root extracts inhibit human prostate and bladder smooth muscle contraction, porcine arterial vasoconstriction, and cytotoxicity of prostate stromal cells.
Frontiers in pharmacology, Vol. 16, 1621346
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Nowacki M, Menezes F, Pykacz E, Popiołek M, Napolitano V, Krishna CK, Kalel VC, Erdmann R, Fröhlich T, Plettenburg O, Sattler M, Popowicz GM, Dawidowski M (2025)
Quantum mechanics-driven structure-activity relationship study of PEX5-PEX14 protein-protein interaction inhibitors based on a dibenzo[b,e]azepin-6(6H)-one scaffold.
European journal of medicinal chemistry, Vol. 298, 117979
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Zhang F, Dorn T, Gnutti B, Anikster Y, Kuebler S, Ahrens-Nicklas R, Gosselin R, Rahman S, Durst R, Zanuttigh E, Güra MA, Poch CM, Meier AB, Laugwitz KL, Schüller HJ, Messias AC, Sibon OC, Finazzi D, Rippert A, Li D, Truxal K, Nandi D, Lampert BC, Yeo M, Gardham A, Nissan B, Horowitz Cederboim S, Moretti A, Iuso A (2025)
Pantethine ameliorates dilated cardiomyopathy features in PPCS deficiency disorder in patients and cell line models.
Communications medicine, Issue 1, Vol. 5, 323
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Dammak I, Hamdi Z, Lamine M, Hajri H, Basiouni S, Ntougias S, Tsiamis G, Yilmaz M, Acheuk F, Emekci M, Eisenreich W, Huber C, Shehata AA, Ben Salem A, Lasram S (2025)
Antifungal and anti-toxigenic activities of Origanum onites and Thymus capitatus essential oils and ethanolic extracts against mycotoxigenic fungi isolated from barley.
Food chemistry, Issue Pt 1, Vol. 493, 145653
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Radziej S, Moldovan A, Klöpfer M, Goebel W, Rudel T, Eisenreich W (2025)
Dual Isotopologue Profiling of Bacterial Pathogens and their Host Cells: Metabolic Adaptation of Human Macrophages and Fallopian Tube Cells to Intracellular Chlamydia trachomatis.
ACS chemical biology, Issue 8, Vol. 20, 1902-1915
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Dürauer S, Kang HS, Wiebeler C, Machida Y, Schnapka DS, Yaneva D, Renz C, Götz MJ, Weickert P, Major AC, Rahmanto AS, Gutenthaler-Tietze SM, Daumann LJ, Beli P, Ulrich HD, Sattler M, Machida YJ, Schwierz N, Stingele J (2025)
Allosteric activation of the SPRTN protease by ubiquitin maintains genome stability.
Nature communications, Issue 1, Vol. 16, 5422
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Hipp C, Mussgnug S, Choudhary P, Kang HS, Asami S, Sastre J, Donau C, Böttcher R, Gemmecker G, Boekhoven J, Förstemann K, Sattler M (2025)
Molecular mechanisms of biomolecular condensate formation in Drosophila melanogaster siRNA biogenesis.
Nucleic acids research, Issue 14, Vol. 53
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Sahoo BR, Watanabe-Nakayama T, Suladze S, Anantharamaiah GM, Reif B, Ramamoorthy A (2025)
Bifunctional nanodisc platforms for studies on self-assembly and amyloid fibrillation.
Chemical communications (Cambridge, England), Issue 66, Vol. 61, 12349-12352
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Gottwald W, Nagel L, Skinner JG, Grashei M, Sühnel S, Setzer N, Eisenreich W, McLean MA, Gallagher FA, Park JM, Ahmadova Z, Gierse M, Karaali S, Knecht S, Schwartz I, Heid I, Topping GJ, van Heijster FHA, Schilling F (2025)
Temperature dependent chemical shifts of pyruvate and lactate enable in vivo hyperpolarized 13C MRSI thermometry.
Npj imaging, Issue 1, Vol. 3, 19
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Bérouti M, Wagner M, Greulich W, Piseddu I, Gärtig J, Hansbauer L, Müller-Hermes C, Heiss M, Pichler A, Tölke AJ, Witte G, Hopfner KP, Anz D, Sattler M, Carell T, Hornung V (2025)
Pseudouridine RNA avoids immune detection through impaired endolysosomal processing and TLR engagement.
Cell, Issue 18, Vol. 188, 4880-4895.e15
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Müller-Hermes C, Piomponi V, Hilber S, Asami S, Kreutz C, Bussi G, Sattler M (2025)
Unique conformational dynamics and protein recognition of A-to-I hyper-edited dsRNA.
Nucleic acids research, Issue 12, Vol. 53
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Rawal S, Kolarić Ð, Bohn S, Kolb D, Pavkov-Keller T, Pritišanac I, Madl T, Desfosses A, Alderson TR (2025)
A histidine switch regulates pH-dependent filament formation by the caspase-9 CARD.
bioRxiv : the preprint server for biology
DOI: 10.1101/2025.06.02.657148, PubMed: 40501686 |
Heker I, Seitz C, Voskuhl L, Kong Y, Erdmann I, Götz F, Hassoun M, Huber C, Eisenreich W, Meckenstock RU (2025)
Chemoorganoautotrophic lifestyle of the anaerobic enrichment culture N47 growing on naphthalene.
Communications biology, Issue 1, Vol. 8, 856
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Du Y, Lv X, Siebenmorgen T, Popowicz G, Feng C, Ma Y, Wang Y (2025)
Enhancing Catalytic Activity of a Baeyer-Villiger monooxygenase from Oceanicola granulosus: Simultaneous Engineering of the Distal Site and Active Site.
Journal of agricultural and food chemistry, Issue 23, Vol. 73, 14453-14466
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Kale OE, Rauanov I, Huber C, Tamalunas A, Stief CG, Eisenreich W, Hennenberg M (2025)
Benzyl Benzoate Isolation from Acridocarpus smeathmannii (DC.) Guill. & Perr Roots and Its Bioactivity on Human Prostate Smooth Muscle Contractions.
Pharmaceuticals (Basel, Switzerland), Issue 5, Vol. 18
DOI: 10.3390/ph18050687, PubMed: 40430506 |
Moldovan A, Krischke M, Huber C, Hans C, Müller MJ, Eisenreich W, Rudel T, Fraunholz MJ (2025)
The AusAB non-ribosomal peptide synthetase of Staphylococcus aureus preferentially generates phevalin in host-mimicking media.
mBio, Issue 6, Vol. 16, e0084524
DOI: 10.1128/mbio.00845-24, PubMed: 40323101 |
Wang Z, Cao G, Collier MP, Qiu X, Broadway-Stringer S, Šaman D, Ng JZY, Sen N, Azad AJ, Hooper C, Zimmermann J, McDonough MA, Brem J, Rabe P, Song H, Alderson TR, Schofield CJ, Bolla JR, Djinovic-Carugo K, Fürst DO, Warscheid B, Degiacomi MT, Allison TM, Hochberg GKA, Robinson CV, Gehmlich K, Benesch JLP (2025)
Filamin C dimerisation is regulated by HSPB7.
Nature communications, Issue 1, Vol. 16, 4090
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Salajegheh Tazerji S, Magalhães Duarte P, Gharieb R, Szarpak L, Pruc M, Rahman MT, J Rodriguez-Morales A, Furqan Ilyas M, Santos Ferreira MN, Singh Malik Y, Kalantari R, Shahrokhabadi A, Jafari N, Shahabinejad F, Maleki Y, Montajeb S, Mehrpouya R, Ahmadi H, Vazir B, Kabir F, Rehman A, Elmi Z, Hajipour P, El-Seedi HR, Eisenreich W, Shehata AA (2025)
Migratory Wave due to Conflicts: Risk of Increased Infection From Zoonotic Diseases.
Transboundary and emerging diseases, Vol. 2025, 5571316
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Zhou J, Ridderbeek K, Zou P, Naden AB, Gaussmann S, Song F, Falter-Braun P, Kay ER, Sattler M, Cui J (2025)
Modular Nanoparticle Platform for Solution-Phase Optical Sensing of Protein-Protein Interactions.
ACS applied optical materials, Issue 3, Vol. 3, 676-688
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Shekhar A, Di Lucrezia R, Jerye K, Korotkov VS, Harmrolfs K, Rox K, Weich HA, Ghai I, Delhommel F, Becher I, Degenhart C, Fansa E, Unger A, Habenberger P, Klebl B, Lukat P, Schmelz S, Henke S, Borgert S, Lang JC, Sasse F, Diestel R, Richter C, Schneider-Daum N, Hinkelmann B, Niemz J, Lehr CM, Jänsch L, Huehn J, Alm R, Savitski M, Welte T, Hesterkamp T, Sattler M, Winterhalter M, Blankenfeldt W, Medina E, Bilitewski U, Dinkel K, Brönstrup M (2025)
Highly potent quinoxalinediones inhibit α-hemolysin and ameliorate Staphylococcus aureus lung infections.
Cell host & microbe, Issue 4, Vol. 33, 560-572.e21
DOI: 10.1016/j.chom.2025.03.006, PubMed: 40168998 |
Oberheide A, van den Oetelaar MCM, Scheele JJA, Borggräfe J, Engelen SFH, Sattler M, Ottmann C, Cossar PJ, Brunsveld L (2025)
Site-specific molecular glues for the 14-3-3/Tau pS214 protein-protein interaction via reversible covalent imine tethering.
RSC medicinal chemistry, Issue 5, Vol. 16, 2190-2201
DOI: 10.1039/d4md00833b, PubMed: 40070456 |
Pettinato E, Steiner TM, Cassens EA, Geisberger T, Seitz C, König S, Eisenreich W, Berg IA (2025)
Propionate metabolism in Desulfurella acetivorans.
Frontiers in microbiology, Vol. 16, 1545849
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Basiouni S, Abel N, Eisenreich W, May-Simera HL, Shehata AA (2025)
Structural Analysis of Cardanol and Its Biological Activities on Human Keratinocyte Cells.
Metabolites, Issue 2, Vol. 15
DOI: 10.3390/metabo15020083, PubMed: 39997708 |
Müller B, Niephaus E, Eisenreich W, Bröker JN, Twyman RM, Prüfer D, Schulze Gronover C (2025)
The cis-prenyltransferase protein family in Taraxacum koksaghyz.
The Plant journal : for cell and molecular biology, Issue 3, Vol. 121, e17233
DOI: 10.1111/tpj.17233, PubMed: 39915980 |
Lenzen B, Rösch F, Legen J, Ruwe H, Kachariya N, Sattler M, Small I, Schmitz-Linneweber C (2025)
The chloroplast RNA-binding protein CP29A supports rbcL expression during cold acclimation.
Proceedings of the National Academy of Sciences of the United States of America, Issue 5, Vol. 122, e2403969122
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Kogut-Günthel MM, Zara Z, Nicoli A, Steuer A, Lopez-Balastegui M, Selent J, Karanth S, Koehler M, Ciancetta A, Abiko LA, Hagn F, Di Pizio A (2025)
The path to the G protein-coupled receptor structural landscape: Major milestones and future directions.
British journal of pharmacology, Issue 14, Vol. 182, 3225-3248
DOI: 10.1111/bph.17314, PubMed: 39209310 |