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Hyperpolarized 13C Metabolic Magnetic Resonance Spectroscopy and Imaging.
Journal of visualized experiments : JoVE, Issue 118
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Wocheslander S, Eisenreich W, Scholz B, Lander V, Engel KH (2016)
Identification of Acyl Chain Oxidation Products upon Thermal Treatment of a Mixture of Phytosteryl/-stanyl Linoleates.
Journal of agricultural and food chemistry, Issue 48, Vol. 64, 9214-9223
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Structural basis for the recognition of spliceosomal SmN/B/B' proteins by the RBM5 OCRE domain in splicing regulation.
eLife, Vol. 5
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Recognition of the 3' splice site RNA by the U2AF heterodimer involves a dynamic population shift.
Proceedings of the National Academy of Sciences of the United States of America, Issue 46, Vol. 113, E7169-E7175
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Observation of Time-Invariant Coherence in a Nuclear Magnetic Resonance Quantum Simulator.
Physical review letters, Issue 16, Vol. 117, 160402
DOI: 10.1103/PhysRevLett.117.160402, PubMed: 27792393 |
Kiske C, Nörenberg S, Ecker M, Ma X, Taniguchi T, Monde K, Eisenreich W, Engel KH (2016)
Reinvestigation of the Absolute Configurations of Chiral β-Mercaptoalkanones Using Vibrational Circular Dichroism and 1H NMR Analysis.
Journal of agricultural and food chemistry, Issue 45, Vol. 64, 8563-8571
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Jagtap PK, Garg D, Kapp TG, Will CL, Demmer O, Lührmann R, Kessler H, Sattler M (2016)
Rational Design of Cyclic Peptide Inhibitors of U2AF Homology Motif (UHM) Domains To Modulate Pre-mRNA Splicing.
Journal of medicinal chemistry, Issue 22, Vol. 59, 10190-10197
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Zierer BK, Rübbelke M, Tippel F, Madl T, Schopf FH, Rutz DA, Richter K, Sattler M, Buchner J (2016)
Importance of cycle timing for the function of the molecular chaperone Hsp90.
Nature structural & molecular biology, Issue 11, Vol. 23, 1020-1028
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Subramaniam S, Erler A, Fu J, Kranz A, Tang J, Gopalswamy M, Ramakrishnan S, Keller A, Grundmeier G, Müller D, Sattler M, Stewart AF (2016)
DNA annealing by Redβ is insufficient for homologous recombination and the additional requirements involve intra- and inter-molecular interactions.
Scientific reports, Vol. 6, 34525
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Corvino A, Severino B, Fiorino F, Frecentese F, Magli E, Perissutti E, Santagada V, Bucci M, Cirino G, Kelly G, Servillo L, Popowicz G, Pastore A, Caliendo G (2016)
Fragment-based de novo design of a cystathionine γ-lyase selective inhibitor blocking hydrogen sulfide production.
Scientific reports, Vol. 6, 34398
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Zhang G, Schilling F, Glaser SJ, Hilty C (2016)
Reaction monitoring using hyperpolarized NMR with scaling of heteronuclear couplings by optimal tracking.
Journal of magnetic resonance (San Diego, Calif. : 1997), Vol. 272, 123-128
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Delaforge E, Milles S, Huang JR, Bouvier D, Jensen MR, Sattler M, Hart DJ, Blackledge M (2016)
Investigating the Role of Large-Scale Domain Dynamics in Protein-Protein Interactions.
Frontiers in molecular biosciences, Vol. 3, 54
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Dallmann A, Beribisky AV, Gnerlich F, Rübbelke M, Schiesser S, Carell T, Sattler M (2016)
Site-Specific Isotope-Labeling of Inosine Phosphoramidites and NMR Analysis of an Inosine-Containing RNA Duplex.
Chemistry (Weinheim an der Bergstrasse, Germany), Issue 43, Vol. 22, 15350-15359
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Eisenreich W, Heuner K (2016)
The life stage-specific pathometabolism of Legionella pneumophila.
FEBS letters, Issue 21, Vol. 590, 3868-3886
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Willenborg J, Koczula A, Fulde M, de Greeff A, Beineke A, Eisenreich W, Huber C, Seitz M, Valentin-Weigand P, Goethe R (2016)
FlpS, the FNR-Like Protein of Streptococcus suis Is an Essential, Oxygen-Sensing Activator of the Arginine Deiminase System.
Pathogens (Basel, Switzerland), Issue 3, Vol. 5
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Bacher A, Chen F, Eisenreich W (2016)
Decoding Biosynthetic Pathways in Plants by Pulse-Chase Strategies Using (13)CO₂ as a Universal Tracer †.
Metabolites, Issue 3, Vol. 6
DOI: 10.3390/metabo6030021, PubMed: 27429012 |
Guo S, Popowicz GM, Li D, Yuan D, Wang Y (2016)
Lid mobility in lipase SMG1 validated using a thiol/disulfide redox potential probe.
FEBS open bio, Issue 5, Vol. 6, 477-83
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Guaitoli G, Raimondi F, Gilsbach BK, Gómez-Llorente Y, Deyaert E, Renzi F, Li X, Schaffner A, Jagtap PK, Boldt K, von Zweydorf F, Gotthardt K, Lorimer DD, Yue Z, Burgin A, Janjic N, Sattler M, Versées W, Ueffing M, Ubarretxena-Belandia I, Kortholt A, Gloeckner CJ (2016)
Structural model of the dimeric Parkinson's protein LRRK2 reveals a compact architecture involving distant interdomain contacts.
Proceedings of the National Academy of Sciences of the United States of America, Issue 30, Vol. 113, E4357-66
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Zheng X, Ramani A, Soni K, Gottardo M, Zheng S, Ming Gooi L, Li W, Feng S, Mariappan A, Wason A, Widlund P, Pozniakovsky A, Poser I, Deng H, Ou G, Riparbelli M, Giuliano C, Hyman AA, Sattler M, Gopalakrishnan J, Li H (2016)
Molecular basis for CPAP-tubulin interaction in controlling centriolar and ciliary length.
Nature communications, Vol. 7, 11874
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Goricanec D, Stehle R, Egloff P, Grigoriu S, Plückthun A, Wagner G, Hagn F (2016)
Conformational dynamics of a G-protein α subunit is tightly regulated by nucleotide binding.
Proceedings of the National Academy of Sciences of the United States of America, Issue 26, Vol. 113, E3629-38
DOI: 10.1073/pnas.1604125113, PubMed: 27298341 |
Scheidler C, Sobotta J, Eisenreich W, Wächtershäuser G, Huber C (2016)
Unsaturated C3,5,7,9-Monocarboxylic Acids by Aqueous, One-Pot Carbon Fixation: Possible Relevance for the Origin of Life.
Scientific reports, Vol. 6, 27595
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Enthart A, Klein C, Dehner A, Coles M, Gemmecker G, Kessler H, Hagn F (2016)
Solution structure and binding specificity of the p63 DNA binding domain.
Scientific reports, Vol. 6, 26707
DOI: 10.1038/srep26707, PubMed: 27225672 |
Görner C, Schrepfer P, Redai V, Wallrapp F, Loll B, Eisenreich W, Haslbeck M, Brück T (2016)
Identification, characterization and molecular adaptation of class I redox systems for the production of hydroxylated diterpenoids.
Microbial cell factories, Vol. 15, 86
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Düwel S, Durst M, Gringeri CV, Kosanke Y, Gross C, Janich MA, Haase A, Glaser SJ, Schwaiger M, Schulte RF, Braren R, Menzel MI (2016)
Multiparametric human hepatocellular carcinoma characterization and therapy response evaluation by hyperpolarized (13) C MRSI.
NMR in biomedicine, Issue 7, Vol. 29, 952-60
DOI: 10.1002/nbm.3561, PubMed: 27195474 |
Orlofsky EM, Kozhoridze G, Lyubenova L, Ostrozhenkova E, Winkler JB, Schröder P, Bacher A, Eisenreich W, Guy M, Golan-Goldhirsh A (2016)
Sexual Dimorphism in the Response of Mercurialis annua to Stress.
Metabolites, Issue 2, Vol. 6
DOI: 10.3390/metabo6020013, PubMed: 27128954 |
Sarkar R, Mainz A, Busi B, Barbet-Massin E, Kranz M, Hofmann T, Reif B (2016)
Immobilization of soluble protein complexes in MAS solid-state NMR: Sedimentation versus viscosity.
Solid state nuclear magnetic resonance, Vol. 76-77, 7-14
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Janowski R, Heinz GA, Schlundt A, Wommelsdorf N, Brenner S, Gruber AR, Blank M, Buch T, Buhmann R, Zavolan M, Niessing D, Heissmeyer V, Sattler M (2016)
Roquin recognizes a non-canonical hexaloop structure in the 3'-UTR of Ox40.
Nature communications, Vol. 7, 11032
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Jung B, Messias AC, Schorpp K, Geerlof A, Schneider G, Saur D, Hadian K, Sattler M, Wanker EE, Hasenöder S, Lickert H (2016)
Novel small molecules targeting ciliary transport of Smoothened and oncogenic Hedgehog pathway activation.
Scientific reports, Vol. 6, 22540
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Jung B, Padula D, Burtscher I, Landerer C, Lutter D, Theis F, Messias AC, Geerlof A, Sattler M, Kremmer E, Boldt K, Ueffing M, Lickert H (2016)
Pitchfork and Gprasp2 Target Smoothened to the Primary Cilium for Hedgehog Pathway Activation.
PloS one, Issue 2, Vol. 11, e0149477
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Prade E, Barucker C, Sarkar R, Althoff-Ospelt G, Lopez del Amo JM, Hossain S, Zhong Y, Multhaup G, Reif B (2016)
Sulindac Sulfide Induces the Formation of Large Oligomeric Aggregates of the Alzheimer's Disease Amyloid-β Peptide Which Exhibit Reduced Neurotoxicity.
Biochemistry, Issue 12, Vol. 55, 1839-49
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Schlundt A, Niessing D, Heissmeyer V, Sattler M (2016)
RNA recognition by Roquin in posttranscriptional gene regulation.
Wiley interdisciplinary reviews. RNA, Issue 4, Vol. 7, 455-69
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Schrepfer P, Buettner A, Goerner C, Hertel M, van Rijn J, Wallrapp F, Eisenreich W, Sieber V, Kourist R, Brück T (2016)
Identification of amino acid networks governing catalysis in the closed complex of class I terpene synthases.
Proceedings of the National Academy of Sciences of the United States of America, Issue 8, Vol. 113, E958-67
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Nokwe CN, Hora M, Zacharias M, Yagi H, Peschek J, Reif B, Goto Y, Buchner J (2016)
A Stable Mutant Predisposes Antibody Domains to Amyloid Formation through Specific Non-Native Interactions.
Journal of molecular biology, Issue 6, Vol. 428, 1315-1332
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Parkinson's disease: Disorder in the court.
Nature, Issue 7588, Vol. 530, 38-9
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Gillmaier N, Schunder E, Kutzner E, Tlapák H, Rydzewski K, Herrmann V, Stämmler M, Lasch P, Eisenreich W, Heuner K (2016)
Growth-related Metabolism of the Carbon Storage Poly-3-hydroxybutyrate in Legionella pneumophila.
The Journal of biological chemistry, Issue 12, Vol. 291, 6471-82
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Carlon A, Ravera E, Hennig J, Parigi G, Sattler M, Luchinat C (2016)
Improved Accuracy from Joint X-ray and NMR Refinement of a Protein-RNA Complex Structure.
Journal of the American Chemical Society, Issue 5, Vol. 138, 1601-10
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Structural basis of RNA recognition and dimerization by the STAR proteins T-STAR and Sam68.
Nature communications, Vol. 7, 10355
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Golestanian S, Sharifi A, Popowicz GM, Azizian H, Foroumadi A, Szwagierczak A, Holak TA, Amanlou M (2016)
Discovery of novel dual inhibitors against Mdm2 and Mdmx proteins by in silico approaches and binding assay.
Life sciences, Vol. 145, 240-6
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Inhibition of Canonical NF-κB Signaling by a Small Molecule Targeting NEMO-Ubiquitin Interaction.
Scientific reports, Vol. 6, 18934
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Kutzner E, Kern T, Felsl A, Eisenreich W, Fuchs TM (2016)
Isotopologue profiling of the listerial N-metabolism.
Molecular microbiology, Issue 2, Vol. 100, 315-27
DOI: 10.1111/mmi.13318, PubMed: 26699934 |
Häuslein I, Manske C, Goebel W, Eisenreich W, Hilbi H (2016)
Pathway analysis using (13) C-glycerol and other carbon tracers reveals a bipartite metabolism of Legionella pneumophila.
Molecular microbiology, Issue 2, Vol. 100, 229-46
DOI: 10.1111/mmi.13313, PubMed: 26691313 |
Kern T, Kutzner E, Eisenreich W, Fuchs TM (2016)
Pathogen-nematode interaction: Nitrogen supply of Listeria monocytogenes during growth in Caenorhabditis elegans.
Environmental microbiology reports, Issue 1, Vol. 8, 20-9
DOI: 10.1111/1758-2229.12344, PubMed: 26478569 |
Emmanouilidis L, Gopalswamy M, Passon DM, Wilmanns M, Sattler M (2016)
Structural biology of the import pathways of peroxisomal matrix proteins.
Biochimica et biophysica acta, Issue 5, Vol. 1863, 804-13
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Giannopoulou EA, Emmanouilidis L, Sattler M, Dodt G, Wilmanns M (2016)
Towards the molecular mechanism of the integration of peroxisomal membrane proteins.
Biochimica et biophysica acta, Issue 5, Vol. 1863, 863-9
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Assländer J, Glaser SJ, Hennig J (2016)
Spin echoes in the regime of weak dephasing.
Magnetic resonance in medicine, Issue 1, Vol. 75, 150-60
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